Denaturalization

From LSWiki

Blue can provide denaturalization services, which is removal of alterations which come by way of spiritual alterations that you can not normally remove. He requires sources of primal energy to perform it, and you can't choose which get removed. See Enas Yorl for a list of primal energy sources, as they seem to overlap.

Denaturalization apparently works in that every artifact given can remove up to ten thousand skillxp worth of affinity skills, but on average favors lower numbers, around a thousand to five thousand. As such, if the affinities you wish to lose were ones you had a very high amount of, you will end up needing to give blue a rather significant amount of items, good luck!